A soon-to-be-completed waterfront Miami Beach mansion is set to hit the market for $27 million, Mansion Global has learned.

Slated to be listed as early as Wednesday, the estate is sequestered on the city’s Sunset Islands, a luxury community spread across four islands. It will be the priciest home listed for sale in the tony enclave, and among the most expensive houses listed across Miami Beach, according to listing records.

Dubbed the Limestone Estate after its stone exterior, construction on the 10,000-square-foot home is wrapping up and expected to be completed in a matter of months, according to the developer James Curnin, founder of Clara Homes.

The house has a “tropical, modern feel,” said Mr. Curnin—who is the great grandson of the late New York City hotel and property developer Jack Parker—and an “organic allure to it that feels very calming.”

Designed by Miami-based architect Max Strang, the six-bedroom estate has floor-to-ceiling glass doors, a library, a home theater, a wine room, a pool and 100 feet of water frontage, according to information provided by the listing agents, Eloy Carmenate and Mick Duchon of Douglas Elliman.

“Close to the water we did a wellness center with an infrared sauna that has these big sliding doors that look out onto the bay,” Mr. Curnin said, adding that the amenity is his favorite spot on the property.

“I always try to build a home that I would want to live in and that I would be accustomed to,” he said. “We don’t do anything outlandish.”

In 2018, Clara Homes acquired the then empty lot for $7.17 million, records with PropertyShark show, and construction began in the summer of 2019 and continued through the height of the coronavirus pandemic.

With construction deemed an essential business during lockdown the project was able to continue with safety protocols in place and without any major delays, according to Mr. Curnin.

The estate also has the good fortune of being completed during a time when South Florida’s high-end single-family home market is booming.

“I got very lucky, [the market has] exploded way beyond my expectations,” Mr. Curnin said.

South Florida has a seemingly enduring appeal among wealthy Northeastern transplants looking for sunshine and tax savings, and demand has only grown during the coronavirus pandemic and the work-from-home and remote-learning policies that have come along with it, Mansion Global previously reported.

Last year, luxury single-family home sales in Miami-Dade County jumped 41.2% year-over-year to 1,447 transactions, according to a February report from the Miami Association of Realtors.